Cytology of Pleural, Pericardial and Peritoneal Cavity Effusions - Effusions and Washes Other Gynecologic Metastases

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Figure 55
Peritoneal effusion: Papillary serous carcinoma of the endometrium. 20X

Figure 56
Peritoneal effusion: Papillary serous carcinoma of the endometrium. 40X

Figures 55-56:
Peritoneal effusion, papillary serous carcinoma of the endometrium. Malignant cells clustered around psammoma bodies.

Figure 57
Peritoneal effusion:
Endometrial adenocarcinoma. Low power photomicrograph shows two separate cell populations. Note the flat sheet at the lower left of uniform, benign cells, many dyshesive tumor cells at lower right, with a large cohesive fragment of tumor cells at upper left.
20X

Figure 58
Peritoneal effusion: Endometrial adenocarcinoma. Malignant cells with features of adenocarcinoma including a mitotic figure, prominent nucleoli, vacuolated cytoplasm and eccentric nuclei. 60X

Figure 59
Pleural effusion: Endometrial adenocarcinoma. 20X

Figure 60
Pleural effusion: Endometrial adenocarcinoma. 40X

Figures 59-60:
Pleural effusion: Endometrial adenocarcinoma.
This pleural effusion contains large clusters of malignant cells. Note increased cell size relative to lymphocytes and mesothelial cells in the background. A discontinuous population is one characteristic of malignancy in body effusions

Figure 61
Pleural effusion: Papillary adenocarcinoma of peritoneal surface. The origin of this tumor is extra-ovarian carcinoma or carcinoma of Müellerian origin. Note distinction from benign cells. 10X

Figure 62
Pleural effusion: Adenocarcinoma. Papillary clusters of malignant cells. 20X

Figure 63
Pleural effusion cell block: Adenocarcinoma. A cell block further highlights the distinct malignant cell population and allows for immunohistochemical analysis of cell markers for differentiation and prognosis. 10X

Figure 64
Pelvic wash: Undifferentiated large cell carcinoma of the cervix. Cytology shows rounded clusters of malignant cells. 60X

Figure 65
Pelvic wash: Carcinoma of the cervix. Magnified view shows vacuolated cytoplasm, prominent nucleoli, and powdery chromatin pattern suggesting an adenocarcinoma. 60X

Figure 66
Pelvic wash: Carcinosarcoma. 20X

Figure 67
Pelvic wash: Carcinosarcoma. 60X

Figures 66-67:
Pelvic wash: Carcinosarcoma.
Clusters of high-grade malignant cells. Look for both malignant epithelial and malignant stromal cell components.

Figure 68
Peritoneal effusion: Fallopian tube adenocarcinoma. 20X

Figure 69
Peritoneal effusion: Fallopian tube adenocarcinoma. 60X