Urinary Tract Cytology – High Grade Urothelial Carcinoma

Figure 31
Catheterized urine, high grade urothelial carcinoma
High grade urothelial carcinomas often are abundantly cellular.
20x

Figure 32
Catheterized urine, high grade urothelial carcinoma
Cells of high grade urothelial carcinoma have high N/C ratios.
40x

Figure 33
Catheterized urine, high grade urothelial carcinoma
Nuclei of high grade urothelial carcinoma are often eccentric with convoluted, thickened membranes.
60x

Figure 34
Urine, high grade urothelial carcinoma
Chromatin in nuclei of high grade carcinoma is coarse, hyperchromatic and often irregularly dispersed.
60x

Figure 35
Urine, high grade urothelial carcinoma
Cells of high grade urothelial carcinoma are pleomorphic and nuclei may contain a prominent, irregular nucleolus.
60x

Figure 36
Urine, high grade urothelial carcinoma
Chromatin in nuclei of high grade carcinoma is coarse and hyperchromatic.
60x

Figure 37
Urine, high grade urothelial carcinoma
Cells are often single with poorly demarcated cyanophilic cytoplasm.
60x

Figure 38
Urine, high grade urothelial carcinomaNuclei may be pointed in high grade urothelial carcinoma.
60x

Figure 39
Bladder washing, high grade urothelial carcinomaAnaplastic cells make high grade urothelial carcinoma relatively easy to diagnose.
60x

Figure 40
Catheterized urine, high grade urothelial carcinoma
Cells of high grade urothelial carcinoma may be clustered.
60x

Figure 41
Urine, high grade urothelial carcinomaNuclei of high grade urothelial carcinoma may have multiple irregular nucleoli.
60x

Figure 42
Urine, high grade urothelial carcinoma
Urothelial tumors may be papillary or non-papillary.
60x