{"id":2159,"date":"2017-08-01T13:07:26","date_gmt":"2017-08-01T13:07:26","guid":{"rendered":"http:\/\/cytologystuff1.wpengine.com\/non-gyn-atlas\/urinary-tract-cytology-low-grade-urothelial-carcinoma\/"},"modified":"2025-02-10T20:04:49","modified_gmt":"2025-02-10T20:04:49","slug":"urinary-tract-cytology-low-grade-urothelial-carcinoma","status":"publish","type":"page","link":"https:\/\/cytologystuff.com\/zh-hans\/non-gyn-atlas\/urinary-tract-cytology-low-grade-urothelial-carcinoma\/","title":{"rendered":"Urinary Tract Cytology &#8211; Low Grade Urothelial Carcinoma"},"content":{"rendered":"<p>[vc_row 0=&#8221;&#8221;][vc_column 0=&#8221;&#8221; offset=&#8221;vc_hidden-lg vc_hidden-md&#8221;][vc_raw_html 0=&#8221;&#8221;]JTNDY2VudGVyJTNFJTNDYSUyMGNsYXNzJTNEJTIyc2hpZnRuYXYtdG9nZ2xlJTIwc2hpZnRuYXYtdG9nZ2xlLWJ1dHRvbiUyMiUyMGRhdGEtc2hpZnRuYXYtdGFyZ2V0JTNEJTIyc2hpZnRuYXYtbWFpbiUyMiUzRSUzQ2klMjBjbGFzcyUzRCUyMmZhJTIwZmEtYmFycyUyMiUzRSUzQyUyRmklM0UlMjBUYWJsZSUyMG9mJTIwQ29udGVudHMlMjAlM0MlMkZhJTNFJTNDJTJGY2VudGVyJTNF[\/vc_raw_html][\/vc_column][\/vc_row][vc_row][vc_column][vc_custom_heading text=&#8221;Urinary Tract Cytology &#8211; Low Grade Urothelial Carcinoma&#8221; font_container=&#8221;tag:h1|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221;][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;2\/3&#8243;][vc_column_text] <a name=\"acknowledgements\"><\/a><\/p>\n<p class=\"subhead\">LOW GRADE UROTHELIAL CARCINOMA AND CARCINOMA IN SITU<\/p>\n<p style=\"padding-left: 7px;\"><a style=\"width: 300px; display: block;\"><img loading=\"lazy\" decoding=\"async\" id=\"selfAssessImg\" src=\"\/images\/button27h.gif\" width=\"300\" height=\"17\" \/><\/a><\/p>\n<div class=\"highslide-gallery\"><strong>Reminder: You may click on any slide image<br \/>\nfor an enlarged view.<\/strong><\/p>\n<div class=\"chartColumnCell\"><a class=\"highslide\" href=\"\/gallery\/images_large\/slide0725.jpg\"><br \/>\n<img decoding=\"async\" title=\"Click to enlarge\" src=\"\/gallery\/images\/slide0725.jpg\" alt=\"Image 2\" border=\"0\" \/><\/a><\/p>\n<div class=\"highslide-caption\">\n<p><strong>Figure 43<\/strong><\/p>\n<p>Voided urine, low grade carcinoma<br \/>\nLow grade urothelial carcinoma is characterized by increased clusters of cells. 20x<\/p>\n<\/div>\n<\/div>\n<div class=\"chartColumnLongCell\"><strong>Figure 43<\/strong><br \/>\nVoided urine, low grade carcinoma<br \/>\nLow grade urothelial carcinoma is characterized by increased clusters of cells.<br \/>\n20x<\/div>\n<div class=\"newRow\"><\/div>\n<div class=\"chartColumnCell\"><a class=\"highslide\" href=\"\/gallery\/images_large\/slide0726.jpg\"><br \/>\n<img decoding=\"async\" title=\"Click to enlarge\" src=\"\/gallery\/images\/slide0726.jpg\" alt=\"Image 3\" border=\"0\" \/><\/a><\/p>\n<div class=\"highslide-caption\">\n<p><strong>Figure 44<\/strong><\/p>\n<p>Voided urine, low grade carcinoma<br \/>\nThe clusters in low grade urothelial carcinoma may or may not be papillary. 40x<\/p>\n<\/div>\n<\/div>\n<div class=\"chartColumnLongCell\"><strong>Figure 44<\/strong><br \/>\nVoided urine, low grade carcinoma<br \/>\nThe clusters in low grade urothelial carcinoma may or may not be papillary.<br \/>\n40x<\/div>\n<div class=\"newRow\"><\/div>\n<div class=\"chartColumnCell\"><a class=\"highslide\" href=\"\/gallery\/images_large\/slide0727.jpg\"><br \/>\n<img decoding=\"async\" title=\"Click to enlarge\" src=\"\/gallery\/images\/slide0727.jpg\" alt=\"Image 3\" border=\"0\" \/><\/a><\/p>\n<div class=\"highslide-caption\"><strong>Figure 45<\/strong><br \/>\nVoided urine, low grade carcinoma<br \/>\nThe cells in the clusters of low grade urothelial carcinoma have high N\/C ratios. 60x<\/div>\n<\/div>\n<div class=\"chartColumnLongCell\"><strong>Figure 45<\/strong><br \/>\nVoided urine, low grade carcinoma<br \/>\nThe cells in the clusters of low grade urothelial carcinoma have high N\/C ratios.<br \/>\n60x<\/div>\n<div class=\"newRow\"><\/div>\n<div class=\"chartColumnCell\"><a class=\"highslide\" href=\"\/gallery\/images_large\/slide0728.jpg\" name=\"pap\"><br \/>\n<img decoding=\"async\" title=\"Click to enlarge\" src=\"\/gallery\/images\/slide0728.jpg\" alt=\"Image 2\" border=\"0\" \/><\/a><\/p>\n<div class=\"highslide-caption\">\n<p><strong>Figure 46<\/strong><\/p>\n<p>Voided urine, low grade carcinoma<br \/>\nNuclei in low grade urothelial carcinoma sometimes bulge out of the cytoplasm. 40x<\/p>\n<\/div>\n<\/div>\n<div class=\"chartColumnLongCell\"><strong>Figure 46<\/strong><br \/>\nVoided urine, low grade carcinoma<br \/>\nNuclei in low grade urothelial carcinoma sometimes bulge out of the cytoplasm.<br \/>\n40x<\/div>\n<div class=\"newRow\"><\/div>\n<div class=\"chartColumnCell\"><a class=\"highslide\" href=\"\/gallery\/images_large\/slide0729.jpg\"><br \/>\n<img decoding=\"async\" title=\"Click to enlarge\" src=\"\/gallery\/images\/slide0729.jpg\" alt=\"Image 3\" border=\"0\" \/><\/a><\/p>\n<div class=\"highslide-caption\"><strong>Figure 47<\/strong><br \/>\nBladder urine, low grade carcinoma<br \/>\nA loose cluster of cells from low grade urothelial carcinoma can be compared to reactive urothelial cells. 20x<\/div>\n<\/div>\n<div class=\"chartColumnLongCell\"><strong>Figure 47<\/strong><br \/>\nBladder urine, low grade carcinoma<br \/>\nA loose cluster of cells from low grade urothelial carcinoma can be compared to reactive urothelial cells. 20x<\/div>\n<div class=\"newRow\"><\/div>\n<div class=\"chartColumnCell\"><a class=\"highslide\" href=\"\/gallery\/images_large\/slide0730.jpg\" name=\"pap\"><br \/>\n<img decoding=\"async\" title=\"Click to enlarge\" src=\"\/gallery\/images\/slide0730.jpg\" alt=\"Image 2\" border=\"0\" \/><\/a><\/p>\n<div class=\"highslide-caption\"><strong>Figure 48<\/strong><br \/>\nBladder urine, low grade carcinoma<br \/>\nNuclei of low grade urothelial carcinoma are irregular and may appear to have notches or grooves. 40x<\/div>\n<\/div>\n<div class=\"chartColumnLongCell\"><strong>Figure 48<\/strong><br \/>\nBladder urine, low grade carcinoma<br \/>\nNuclei of low grade urothelial carcinoma are irregular and may appear to have notches or grooves.<br \/>\n40x<\/div>\n<div class=\"newRow\"><\/div>\n<div class=\"chartColumnCell\"><a class=\"highslide\" href=\"\/gallery\/images_large\/slide0731.jpg\"><br \/>\n<img decoding=\"async\" title=\"Click to enlarge\" src=\"\/gallery\/images\/slide0731.jpg\" alt=\"Image 3\" border=\"0\" \/><\/a><\/p>\n<div class=\"highslide-caption\"><strong>Figure 49<\/strong><br \/>\nCystoscopy urine, low grade carcinoma<br \/>\nCompare the normal urothelial on the right to the crowded cluster on the left. 40x<\/div>\n<\/div>\n<div class=\"chartColumnLongCell\"><strong>Figure 49<\/strong><br \/>\nCystoscopy urine, low grade carcinoma<br \/>\nCompare the normal urothelial on the right to the crowded cluster on the left.<br \/>\n40x<\/div>\n<div class=\"newRow\"><\/div>\n<div class=\"chartColumnCell\"><a class=\"highslide\" href=\"\/gallery\/images_large\/slide0732.jpg\"><br \/>\n<img decoding=\"async\" title=\"Click to enlarge\" src=\"\/gallery\/images\/slide0732.jpg\" alt=\"Image 3\" border=\"0\" \/><\/a><\/p>\n<div class=\"highslide-caption\"><strong>Figure 50<\/strong><br \/>\nUrine, low grade carcinoma<br \/>\nCells of low grade urothelial carcinoma may be in small groups with some single cells. 20x<\/div>\n<\/div>\n<div class=\"chartColumnLongCell\"><strong>Figure 50<\/strong><br \/>\nUrine, low grade carcinoma<br \/>\nCells of low grade urothelial carcinoma may be in small groups with some single cells.<br \/>\n20x<\/div>\n<div class=\"newRow\"><\/div>\n<div class=\"chartColumnCell\"><a class=\"highslide\" href=\"\/gallery\/images_large\/slide0733.jpg\"><br \/>\n<img decoding=\"async\" title=\"Click to enlarge\" src=\"\/gallery\/images\/slide0733.jpg\" alt=\"Image 3\" border=\"0\" \/><\/a><\/p>\n<div class=\"highslide-caption\"><strong>Figure 51<\/strong><br \/>\nUrine, low grade carcinoma<br \/>\nNucleoli are usually indistinct or absent in low grade urothelial carcinoma. 40x<\/div>\n<\/div>\n<div class=\"chartColumnLongCell\"><strong>Figure 51<\/strong><br \/>\nUrine, low grade carcinoma<br \/>\nNucleoli are usually indistinct or absent in low grade urothelial carcinoma.<br \/>\n40x<\/div>\n<div class=\"newRow\"><\/div>\n<div class=\"chartColumnCell\"><a class=\"highslide\" href=\"\/gallery\/images_large\/slide0734.jpg\" name=\"pap\"><br \/>\n<img decoding=\"async\" title=\"Click to enlarge\" src=\"\/gallery\/images\/slide0734.jpg\" alt=\"Image 2\" border=\"0\" \/><\/a><\/p>\n<div class=\"highslide-caption\"><strong>Figure 52<\/strong><br \/>\nVoided urine, low grade carcinoma<br \/>\nChromatin in low grade urothelial carcinoma is usually granular and evenly distributed. 60x<\/div>\n<\/div>\n<div class=\"chartColumnLongCell\"><strong>Figure 52<\/strong><br \/>\nVoided urine, low grade carcinomaChromatin in low grade urothelial carcinoma is usually granular and evenly distributed.<br \/>\n60x<\/p>\n<\/div>\n<div class=\"newRow\"><\/div>\n<div class=\"chartColumnCell\"><a class=\"highslide\" href=\"\/gallery\/images_large\/slide0735.jpg\"><br \/>\n<img decoding=\"async\" title=\"Click to enlarge\" src=\"\/gallery\/images\/slide0735.jpg\" alt=\"Image 3\" border=\"0\" \/><\/a><\/p>\n<div class=\"highslide-caption\"><strong>Figure 53<\/strong><br \/>\nUrine, urothelial carcinoma in situ<br \/>\nCytologic features of carcinoma in situ are similar to those of high grade urothelial carcinoma. 60x<\/div>\n<\/div>\n<div class=\"chartColumnLongCell\"><strong>Figure 53<\/strong><br \/>\nUrine, urothelial carcinoma in situ<br \/>\nCytologic features of carcinoma in situ are similar to those of high grade urothelial carcinoma.<br \/>\n60x<\/div>\n<div class=\"newRow\"><\/div>\n<div class=\"chartColumnCell\"><a class=\"highslide\" href=\"\/gallery\/images_large\/slide0736.jpg\"><br \/>\n<img decoding=\"async\" title=\"Click to enlarge\" src=\"\/gallery\/images\/slide0736.jpg\" alt=\"Image 3\" border=\"0\" \/><\/a><\/p>\n<div class=\"highslide-caption\"><strong>Figure 54<\/strong><br \/>\nUrine, urothelial carcinoma in situ<br \/>\nInvasion can be suspected when tumor cells are associated with diathesis, but an unequivocal diagnosis of CIS versus invasion cannot be rendered by cytology alone. 40x<\/div>\n<\/div>\n<div class=\"chartColumnLongCell\"><strong>Figure 54<\/strong><br \/>\nUrine, urothelial carcinoma in situ<br \/>\nInvasion can be suspected when tumor cells are associated with diathesis, but an unequivocal diagnosis of CIS versus invasion cannot be rendered by cytology alone.<br \/>\n40x<\/div>\n<\/div>\n<div 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