{"id":2138,"date":"2017-08-01T12:45:40","date_gmt":"2017-08-01T12:45:40","guid":{"rendered":"http:\/\/cytologystuff1.wpengine.com\/non-gyn-atlas\/respiratory-cytology-squamous-cell-carcinoma\/"},"modified":"2025-02-10T20:04:46","modified_gmt":"2025-02-10T20:04:46","slug":"respiratory-cytology-squamous-cell-carcinoma","status":"publish","type":"page","link":"https:\/\/cytologystuff.com\/zh-hans\/non-gyn-atlas\/respiratory-cytology-squamous-cell-carcinoma\/","title":{"rendered":"Respiratory Cytology – Squamous Cell Carcinoma"},"content":{"rendered":"

[vc_row 0=””][vc_column 0=”” offset=”vc_hidden-lg vc_hidden-md”][vc_raw_html 0=””]JTNDY2VudGVyJTNFJTNDYSUyMGNsYXNzJTNEJTIyc2hpZnRuYXYtdG9nZ2xlJTIwc2hpZnRuYXYtdG9nZ2xlLWJ1dHRvbiUyMiUyMGRhdGEtc2hpZnRuYXYtdGFyZ2V0JTNEJTIyc2hpZnRuYXYtbWFpbiUyMiUzRSUzQ2klMjBjbGFzcyUzRCUyMmZhJTIwZmEtYmFycyUyMiUzRSUzQyUyRmklM0UlMjBUYWJsZSUyMG9mJTIwQ29udGVudHMlMjAlM0MlMkZhJTNFJTNDJTJGY2VudGVyJTNF[\/vc_raw_html][\/vc_column][\/vc_row][vc_row][vc_column][vc_custom_heading text=”Respiratory Cytology – Squamous Cell Carcinoma” font_container=”tag:h1|text_align:center” use_theme_fonts=”yes”][\/vc_column][\/vc_row][vc_row][vc_column width=”2\/3″][vc_column_text]<\/p>\n

SQUAMOUS CELL CARCINOMA<\/p>\n

<\/a><\/p>\n

\n

Reminder: You may click on any slide image
\nfor an enlarged view.<\/strong><\/p>\n


\n\"Image<\/a><\/p>\n
Figure 76<\/strong>
\nSputum
\nOrangeophilic cells with hyperchromatic nuclei are suspicious for squamous cell carcinoma. 60x<\/div>\n<\/div>\n
Figure 76<\/strong>
\nSputum
\nOrangeophilic cells with hyperchromatic nuclei are suspicious for squamous cell carcinoma.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 77<\/strong>
\nSputum
\nAtypical squamous metaplastic cells are considered suspicious for squamous cell carcinoma as their nuclei become hyperchromatic and angulated. 60X<\/div>\n<\/div>\n
Figure 77<\/strong>
\nSputum
\nAtypical squamous metaplastic cells are considered suspicious for squamous cell carcinoma as their nuclei become hyperchromatic and angulated.
\n60X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 78<\/strong>
\nBronchial wash
\nAt lower magnification a large cell, highly suspicious for squamous cell carcinoma, is present. 20x<\/div>\n<\/div>\n
Figure 78<\/strong>
\nBronchial wash
\nAt lower magnification a large cell, highly suspicious for squamous cell carcinoma, is present.
\n20x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 79<\/strong>
\nBronchial wash
\nNumerous atypical squamous cells with polys are present in this cluster of cells from a case of squamous cell carcinoma. 20x<\/div>\n<\/div>\n
Figure 79<\/strong>
\nBronchial wash
\nNumerous atypical squamous cells with polys are present in this cluster of cells from a case of squamous cell carcinoma.
\n20x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 80<\/strong>
\nBronchial wash
\nSpindle-shaped and filamentous cells from squamous cell carcinoma. 20x<\/div>\n<\/div>\n
Figure 80<\/strong>
\nBronchial wash
\nSpindle-shaped and filamentous cells from squamous cell carcinoma.
\n20x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 81<\/strong>
\nBronchial wash
\nHigher magnification of spindle cells from squamous cell carcinoma 40x<\/div>\n<\/div>\n
Figure 81<\/strong>
\nBronchial wash
\nHigher magnification of spindle cells from squamous cell carcinoma
\n40x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 82<\/strong>
\nBronchial wash
\nNot all cells of squamous cell carcinomas are orangeophilic. Basophilic staining may be seen. 60x<\/div>\n<\/div>\n
Figure 82<\/strong>
\nBronchial wash
\nNot all cells of squamous cell carcinomas are orangeophilic. Basophilic staining may be seen.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 83<\/strong>
\nBronchial wash
\nA pearl of keratinized cells from a case of squamous cell carcinoma. 60x<\/div>\n<\/div>\n
Figure 83<\/strong>
\nBronchial wash
\nA pearl of keratinized cells from a case of squamous cell carcinoma.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 84<\/strong>
\nBronchial wash
\nLower magnification showing squamous cell carcinoma in the upper left portion of the field. 20x<\/div>\n<\/div>\n
Figure 84<\/strong>
\nBronchial wash
\nLower magnification showing squamous cell carcinoma in the upper left portion of the field.
\n20x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 85<\/strong>
\nBronchial wash
\nThis cluster of cells from squamous cell carcinoma has marked nuclear atypia. The dense cytoplasm and sharp cytoplasmic border indicates squamous differentiation. 60x<\/div>\n<\/div>\n
Figure 85<\/strong>
\nBronchial wash
\nThis cluster of cells from squamous cell carcinoma has marked nuclear atypia. The dense cytoplasm and sharp cytoplasmic border indicates squamous differentiation.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 86<\/strong>
\nBronchial wash
\nTadpole shaped cells maybe seen in squamous cell carcinoma. 20x<\/div>\n<\/div>\n
Figure 86<\/strong>
\nBronchial wash
\nTadpole shaped cells maybe seen in squamous cell carcinoma.
\n20x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 87<\/strong>
\nBronchial wash
\nThis cluster contains many abnormal cells. Their nuclear detail is seen at the periphery of the cluster. 20x<\/div>\n<\/div>\n
Figure 87<\/strong>
\nBronchial wash
\nThis cluster contains many abnormal cells. Their nuclear detail is seen at the periphery of the cluster.
\n20x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 88<\/strong>
\nBronchial wash
\nWhen in a cluster, it may be difficult to distinguish the cells of squamous cell carcinoma from adenocarcinoma. 20x<\/div>\n<\/div>\n
Figure 88<\/strong>
\nBronchial wash
\nWhen in a cluster, it may be difficult to distinguish the cells of squamous cell carcinoma from adenocarcinoma.
\n20x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 89<\/strong>
\nBronchial wash
\nPoorly differentiated squamous cell carcinoma. 60x<\/div>\n<\/div>\n
Figure 89<\/strong>
\nBronchial wash
\nPoorly differentiated squamous cell carcinoma.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 90<\/strong>
\nBronchial wash
\nCell borders in poorly-differentiated squamous cell carcinoma are sharper than those of adenocarcinoma. Nucleoli are multiple, and eccentric. 40x<\/div>\n<\/div>\n
Figure 90<\/strong>
\nBronchial wash
\nCell borders in poorly-differentiated squamous cell carcinoma are sharper than those of adenocarcinoma. Nucleoli are multiple, and eccentric.
\n40x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 91<\/strong>
\nBronchial wash
\nPoorly differentiated squamous cell carcinoma. Keratin material is present in vacuoles in the cytoplasm. 60x<\/div>\n<\/div>\n
Figure 91<\/strong>
\nBronchial wash
\nPoorly differentiated squamous cell carcinoma. Keratin material is present in vacuoles in the cytoplasm.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 92<\/strong>
\nBronchial wash
\nCareful study of a poorly differentiated squamous cell carcinoma shows scattered keratinization. 40x<\/div>\n<\/div>\n
Figure 92<\/strong>
\nBronchial wash
\nCareful study of a poorly differentiated squamous cell carcinoma shows scattered keratinization.
\n40x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 93<\/strong>
\nBronchial wash
\nLow magnification shows atypical keratinized cells in squamous cell carcinoma. 20x<\/div>\n<\/div>\n
Figure 93<\/strong>
\nBronchial wash
\nLow magnification shows atypical keratinized cells in squamous cell carcinoma.
\n20x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 94<\/strong>
\nBronchial wash
\nHigh magnification reveals bizarre nuclei, admixed with necrotic debris. 60x<\/div>\n<\/div>\n
Figure 94<\/strong>
\nBronchial wash
\nHigh magnification reveals bizarre nuclei, admixed with necrotic debris.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 95<\/strong>
\nBronchial wash
\nDeeply keratinized cells are seen in this squamous cell carcinoma. 60x<\/div>\n<\/div>\n
Figure 95<\/strong>
\nBronchial wash
\nDeeply keratinized cells are seen in this squamous cell carcinoma.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 96<\/strong>
\nBronchial wash
\nBizarre cell shapes with sharply angulated nuclei in this squamous cell carcinoma. 60x<\/div>\n<\/div>\n
Figure 96<\/strong>
\nBronchial wash
\nBizarre cell shapes with sharply angulated nuclei in this squamous cell carcinoma.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 97<\/strong>
\nBronchial brushing
\nLow magnification of a bronchial brushing of a squamous cell carcinoma. 20x<\/div>\n<\/div>\n
Figure 97<\/strong>
\nBronchial brushing
\nLow magnification of a bronchial brushing of a squamous cell carcinoma.
\n20x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 98<\/strong>
\nBronchial brushing
\nThe cells in this squamous cell carcinoma are well differentiated. 60x<\/div>\n<\/div>\n
Figure 98<\/strong>
\nBronchial brushing
\nThe cells in this squamous cell carcinoma are well differentiated.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 99<\/strong>
\nBronchial brushing
\nMildly reactive bronchial epithelium. Compare this to the previous photograph. 60x<\/div>\n<\/div>\n
Figure 99<\/strong>
\nBronchial brushing
\nMildly reactive bronchial epithelium. Compare this to the previous photograph.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 100<\/strong>
\nBronchial brushing
\nGiant tumor cells are present in this squamous cell carcinoma 60x<\/div>\n<\/div>\n
Figure 100<\/strong>
\nBronchial brushing
\nGiant tumor cells are present in this squamous cell carcinoma
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 101<\/strong>
\nLeft upper lobe brushing
\nLow magnification of a squamous cell carcinoma. 20x<\/div>\n<\/div>\n
Figure 101<\/strong>
\nLeft upper lobe brushing
\nLow magnification of a squamous cell carcinoma.
\n20x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 102<\/strong>
\nLeft upper lobe brushing
\nSheets of tumor cells are a feature of squamous cell carcinoma. 40x<\/div>\n<\/div>\n
Figure 102<\/strong>
\nLeft upper lobe brushing
\nSheets of tumor cells are a feature of squamous cell carcinoma.
\n40x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 103<\/strong>
\nLeft upper lobe brushing
\nNote in this case the variable number and position of nucleoli. 60x<\/div>\n<\/div>\n
Figure 103<\/strong>
\nLeft upper lobe brushing
\nNote in this case the variable number and position of nucleoli.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 104<\/strong>
\nLeft upper lobe brushing
\nThe cell on the right shows irregular nuclear shape, clumped chromatin and multiple irregularly shaped nucleoli. There are masses of keratin in the cytoplasm indicating squamous differentiation. 60x<\/div>\n<\/div>\n
Figure 104<\/strong>
\nLeft upper lobe brushing
\nThe cell on the right shows irregular nuclear shape, clumped chromatin and multiple irregularly shaped nucleoli. There are masses of keratin in the cytoplasm indicating squamous differentiation.
\n60x<\/div>\n<\/div>\n
<\/div>\n

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