{"id":2075,"date":"2017-07-31T19:31:02","date_gmt":"2017-07-31T19:31:02","guid":{"rendered":"http:\/\/cytologystuff1.wpengine.com\/non-gyn-atlas\/negative-washes\/"},"modified":"2025-02-10T20:04:37","modified_gmt":"2025-02-10T20:04:37","slug":"negative-washes","status":"publish","type":"page","link":"https:\/\/cytologystuff.com\/zh-hans\/non-gyn-atlas\/negative-washes\/","title":{"rendered":"Negative Washes"},"content":{"rendered":"

[vc_row 0=””][vc_column 0=”” offset=”vc_hidden-lg vc_hidden-md”][vc_raw_html 0=””]JTNDY2VudGVyJTNFJTNDYSUyMGNsYXNzJTNEJTIyc2hpZnRuYXYtdG9nZ2xlJTIwc2hpZnRuYXYtdG9nZ2xlLWJ1dHRvbiUyMiUyMGRhdGEtc2hpZnRuYXYtdGFyZ2V0JTNEJTIyc2hpZnRuYXYtbWFpbiUyMiUzRSUzQ2klMjBjbGFzcyUzRCUyMmZhJTIwZmEtYmFycyUyMiUzRSUzQyUyRmklM0UlMjBUYWJsZSUyMG9mJTIwQ29udGVudHMlMjAlM0MlMkZhJTNFJTNDJTJGY2VudGVyJTNF[\/vc_raw_html][\/vc_column][\/vc_row][vc_row][vc_column][vc_custom_heading text=”Cytology of Pleural, Pericardial and Peritoneal Cavity Effusions – Negative Washes” font_container=”tag:h1|text_align:center” use_theme_fonts=”yes”][\/vc_column][\/vc_row][vc_row el_id=”acknowledgements”][vc_column width=”2\/3″][vc_column_text]<\/a><\/p>\n

NEGATIVE WASHES<\/p>\n

<\/a><\/p>\n

\n

Reminder: You may click on any slide image
\nfor an enlarged view.<\/strong><\/p>\n


\n\"Image<\/a><\/p>\n
\n

Figure 13<\/strong><\/p>\n

Peritoneal wash: Benign. 20X<\/p>\n<\/div>\n<\/div>\n

Figure 13
\n<\/strong>Peritoneal wash:
\nBenign.
\n20X<\/div>\n
<\/div>\n

For peritoneal washings the surgeon performs an irrigation or barbitage to collect cells for analysis. Pelvic mesothelial cells may be shed in broad and flat sheets. Sometimes the sheets fold so that overlapping of cells is evident. The benign nature of these mesothelial cells is obvious by their uniform arrangement and appearance.<\/p>\n

 <\/p>\n


\n\"Image<\/a><\/p>\n
\n

Figure 14<\/strong><\/p>\n

Peritoneal wash: Benign mesothelial cells in a cluster. 40X<\/p>\n<\/div>\n<\/div>\n

Figure 14
\n<\/strong> Peritoneal wash:
\nBenign mesothelial cells in a cluster.
\n40X<\/div>\n
<\/div>\n

Benign mesothelial cells from a peritoneal washing may also appear rounded up into a more three-dimensional group with some overlap. Close examination reveals uniform cells with benign nuclear features.<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 15<\/strong>
\nPeritoneal wash: Reactive mesothelial cells. 40X<\/div>\n<\/div>\n
Figure 15
\n<\/strong>
\nPeritoneal wash:
\nReactive mesothelial cells.
\n40X<\/div>\n
<\/div>\n

This group of benign mesothelial cells also demonstrates slight overlapping. Clusters of benign mesothelial cells have a scalloped, or hobnail border, in contrast to the smooth border typically found in clusters of adenocarcinoma.<\/p>\n

 <\/p>\n


\n\"Image<\/a><\/p>\n
Figure 16<\/strong>
\nPelvic wash: Benign mesothelial cells. 20X<\/div>\n<\/div>\n
Figure 16
\n<\/strong>Pelvic wash:
\nBenign mesothelial cells.
\n20X<\/div>\n
<\/div>\n

A flat sheet of evenly spaced mesothelial cells in a honeycombed pattern.<\/p>\n

 <\/p>\n


\n\"Image<\/a><\/p>\n
\n

Figure 17<\/strong><\/p>\n

Pelvic wash: Benign mesothelial cells. 40X<\/p>\n<\/div>\n<\/div>\n

Figure 17
\n<\/strong> Pelvic wash:
\nBenign mesothelial cells.
\n40X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
\n

Figure 18<\/strong><\/p>\n

Pelvic wash: Benign mesothelial cells. 20X<\/p>\n<\/div>\n<\/div>\n

Figure 18
\n<\/strong>Pelvic wash:
\nBenign mesothelial cells.
\n20X<\/div>\n
<\/div>\n

Figures 17 and 18<\/strong> show large sheets of mesothelial cells. Nuclei are vesicular and uniform with small or inconspicuous nucleoli.<\/p>\n


\n\"Image<\/a><\/p>\n
\n

Figure 19<\/strong><\/p>\n

Pelvic wash: Negative. 40X<\/p>\n<\/div>\n<\/div>\n

Figure 19
\n<\/strong> Pelvic wash:
\nNegative.
\n40X<\/div>\n
<\/div>\n

Mesothelial cells can also have a cuboidal appearance with more condensed cytoplasm. Again, note the cohesive sheet of cells with uniformity of nuclei throughout.<\/p>\n


\n\"Image<\/a><\/p>\n
\n

Figure 20<\/strong><\/p>\n

Peritoneal wash: Artifacts. 20X<\/p>\n<\/div>\n<\/div>\n

Figure 20
\n<\/strong> Peritoneal wash:
\nArtifacts.
\n20X<\/div>\n
<\/div>\n

Cholesterol and other types of crystals may be seen in peritoneal washes and fluids from other body sites.<\/p>\n

 <\/p>\n

\n


\n\"Image<\/a><\/p>\n

\n

Figure 21<\/strong><\/p>\n

Peritoneal wash: Artifacts. 60X<\/p>\n<\/div>\n<\/div>\n

Figure 21
\n<\/strong> Peritoneal wash:
\nArtifacts.
\n60X<\/div>\n<\/div>\n
<\/div>\n

Reactive mesothelial cells containing starch granules are indicative of glove powder contamination from a prior laparotomy. Starch granules may also contaminate the specimen via the gloves of the technician processing the specimen.[\/vc_column_text][vc_column_text css=”.vc_custom_1500390293825{margin-top: 30px !important;}” el_class=”back-to-top”]Back to Top<\/a><\/strong>[\/vc_column_text][\/vc_column][vc_column width=”1\/3″ offset=”vc_hidden-sm vc_hidden-xs”][vc_widget_sidebar sidebar_id=”consulting-right-sidebar”][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"

[vc_row 0=””][vc_column 0=”” of<\/p>\n","protected":false},"author":7,"featured_media":0,"parent":1947,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ngg_post_thumbnail":0,"footnotes":""},"class_list":["post-2075","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/pages\/2075","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=2075"}],"version-history":[{"count":0,"href":"https:\/\/cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/pages\/2075\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/pages\/1947"}],"wp:attachment":[{"href":"https:\/\/cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=2075"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}