{"id":1983,"date":"2017-07-31T20:06:49","date_gmt":"2017-07-31T20:06:49","guid":{"rendered":"http:\/\/cytologystuff1.wpengine.com\/non-gyn-atlas\/effusions-metastatic-gastrointestinal-malignancy\/"},"modified":"2025-02-10T20:03:07","modified_gmt":"2025-02-10T20:03:07","slug":"effusions-metastatic-gastrointestinal-malignancy","status":"publish","type":"page","link":"https:\/\/cytologystuff.com\/zh-hans\/non-gyn-atlas\/effusions-metastatic-gastrointestinal-malignancy\/","title":{"rendered":"Effusions – Metastatic Gastrointestinal Malignancy"},"content":{"rendered":"

[vc_row 0=””][vc_column 0=”” offset=”vc_hidden-lg vc_hidden-md”][vc_raw_html 0=””]JTNDY2VudGVyJTNFJTNDYSUyMGNsYXNzJTNEJTIyc2hpZnRuYXYtdG9nZ2xlJTIwc2hpZnRuYXYtdG9nZ2xlLWJ1dHRvbiUyMiUyMGRhdGEtc2hpZnRuYXYtdGFyZ2V0JTNEJTIyc2hpZnRuYXYtbWFpbiUyMiUzRSUzQ2klMjBjbGFzcyUzRCUyMmZhJTIwZmEtYmFycyUyMiUzRSUzQyUyRmklM0UlMjBUYWJsZSUyMG9mJTIwQ29udGVudHMlMjAlM0MlMkZhJTNFJTNDJTJGY2VudGVyJTNF[\/vc_raw_html][\/vc_column][\/vc_row][vc_row][vc_column][vc_custom_heading text=”Cytology of Pleural, Pericardial and Peritoneal Cavity Effusions – Effusions – Metastatic Gastrointestinal Malignancy” font_container=”tag:h1|text_align:center” use_theme_fonts=”yes”][\/vc_column][\/vc_row][vc_row el_id=”acknowledgements”][vc_column width=”2\/3″][vc_column_text]<\/a><\/p>\n

EFFUSIONS – METASTATIC GASTROINTESTINAL MALIGNANCY<\/p>\n

<\/a><\/p>\n

\n

Reminder: You may click on any slide image
\nfor an enlarged view.<\/strong><\/p>\n


\n\"Image<\/a><\/p>\n
Figure 93<\/strong>
\nPeritoneal effusion: Gastric adenocarcinoma. Cells with malignant features are present as a distinct population. Some may exhibit nuclear displacement by a large secretory vacuole, a “signet ring” cell. Origin from one part of the GI tract over another cannot be easily ascertained. 60x<\/div>\n<\/div>\n
Figure 93<\/strong>
\nPeritoneal effusion:
\nGastric adenocarcinoma. Cells with malignant features are present as a distinct population. Some may exhibit nuclear displacement by a large secretory vacuole, a “signet ring” cell. Origin from one part of the GI tract over another cannot be easily ascertained.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 94<\/strong>
\nPeritoneal effusion: Cell block, gastric adenocarcinoma. The cell block contains cells with similar malignant features as those seen in the ThinPrep slide of the effusion. 40x<\/div>\n<\/div>\n
Figure 94<\/strong>
\nPeritoneal effusion:
\nCell block, gastric adenocarcinoma. The cell block contains cells with similar malignant features as those seen in the ThinPrep slide of the effusion.
\n40x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 95<\/strong>
\nPeritoneal effusion: Poorly differentiated gastric carcinoma. Malignant cells stand out easily from the benign cells in the background. 20x<\/div>\n<\/div>\n
Figure 95<\/strong>
\nPeritoneal effusion:
\nPoorly differentiated gastric carcinoma. Malignant cells stand out easily from the benign cells in the background.
\n20x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 96<\/strong>
\nPeritoneal effusion: Poorly differentiated gastric carcinoma. The enlarged, eccentric nuclei exhibit irregular nuclear membranes and prominent nucleoli. 60x<\/div>\n<\/div>\n
Figure 96<\/strong>
\nPeritoneal effusion:
\nPoorly differentiated gastric carcinoma. The enlarged, eccentric nuclei exhibit irregular nuclear membranes and prominent nucleoli.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 97<\/strong>
\nPeritoneal effusion: Gastric carcinoma. Malignant peritoneal effusion in a case of metastatic gastric carcinoma. A loose cluster of malignant cells with pleomorphic nuclei and multiple mitotic figures. 60x<\/div>\n<\/div>\n
Figure 97<\/strong>
\nPeritoneal effusion:
\nGastric carcinoma. Malignant peritoneal effusion in a case of metastatic gastric carcinoma. A loose cluster of malignant cells with pleomorphic nuclei and multiple mitotic figures.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 98<\/strong>
\nPleural effusion: Gastric carcinoma. 40x<\/div>\n<\/div>\n
Figure 98<\/strong>
\nPleural effusion:
\nGastric carcinoma.
\n40x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 99<\/strong>
\nPleural effusion: Gastric carcinoma. 60x<\/div>\n<\/div>\n
Figure 99<\/strong>
\nPleural effusion:
\nGastric carcinoma.
\n60x<\/div>\n
<\/div>\n

Fig 98-99: Pleural effusion: Gastric carcinoma.<\/strong>
\nMalignant glandular cells arranged in a dense, rounded cluster. Note that the surface cells maintain cell polarity with apical cytoplasm. The nuclei are irregular with prominent nucleoli.<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 100<\/strong>
\nAbdominal wash: Colon adenocarcinoma. 20x<\/div>\n<\/div>\n
Figure 100<\/strong>
\nAbdominal wash:
\nColon adenocarcinoma.
\n20x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 101<\/strong>
\nAbdominal wash: Colon adenocarcinoma. 40x<\/div>\n<\/div>\n
Figure 101<\/strong>
\nAbdominal wash:
\nColon adenocarcinoma.
\n40x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 102<\/strong>
\nAbdominal wash: Colon adenocarcinoma. 60x<\/div>\n<\/div>\n
Figure 102<\/strong>
\nAbdominal wash:
\nColon adenocarcinoma.
\n60x<\/div>\n
<\/div>\n

Fig 101-102: Abdominal wash: Colon adenocarcinoma.<\/strong>
\nAbdominal washings showing malignant glandular cells. This case is from a patient with colon carcinoma. The papillary clusters of cells show obvious features of an adenocarcinoma, but no distinct clues as to the origin of the tumor.<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 103<\/strong>
\nPeritoneal effusion: Hepatocellular carcinoma. 20x<\/div>\n<\/div>\n
Figure 103<\/strong>
\nPeritoneal effusion:
\nHepatocellular carcinoma.
\n20x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 104<\/strong>
\nPeritoneal effusion: Hepatocellular carcinoma. 60x<\/div>\n<\/div>\n
Figure 104<\/strong>
\nPeritoneal effusion:
\nHepatocellular carcinoma.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 105<\/strong>
\nPeritoneal effusion: Hepatocellular carcinoma. 60x<\/div>\n<\/div>\n
Figure 105<\/strong>
\nPeritoneal effusion:
\nHepatocellular carcinoma.
\n60x<\/div>\n
<\/div>\n

Fig 103-105: Peritoneal effusion:Hepatocellular carcinoma.<\/strong>
\nHepatoma may shed malignant cells into the peritoneal effusion. The cells exhibit granular cytoplasm and centrally placed, abnormal nuclei. Distinction from adenocarcinoma may be difficult.<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 106<\/strong>
\nPeritoneal effusion: Cholangiocarcinoma. 20x<\/div>\n<\/div>\n
Figure 106<\/strong>
\nPeritoneal effusion:
\nCholangiocarcinoma.
\n20x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 107<\/strong>
\nPeritoneal effusion: Cholangiocarcinoma. 40x<\/div>\n<\/div>\n
Figure 107<\/strong>
\nPeritoneal effusion:
\nCholangiocarcinoma.
\n40x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 108<\/strong>
\nPeritoneal effusion: Cholangiocarcinoma. 60x<\/div>\n<\/div>\n
Figure 108<\/strong>
\nPeritoneal effusion:
\nCholangiocarcinoma.
\n60x<\/div>\n
<\/div>\n

Fig 106-108: Peritoneal effusion: Cholangiocarcinoma.<\/strong>
\nCholangiocarcinoma, either from an intra-hepatic source or from an extra-hepatic biliary tree, may look like adenocarcinoma from elsewhere in the GI tract. By exclusion of other sources through endoscopy, ultrasonography and\/orCT imaging, the location may be determined.<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 109<\/strong>
\nPeritoneal wash: Suspicious for pancreatic carcinoma. 60x<\/div>\n<\/div>\n
Figure 109<\/strong>
\nPeritoneal wash:
\nSuspicious for pancreatic carcinoma.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 110<\/strong>
\nPeritoneal wash: Suspicious for pancreatic carcinoma. 60x<\/div>\n<\/div>\n
Figure 110<\/strong>
\nPeritoneal wash:
\nSuspicious for pancreatic carcinoma.
\n60x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 111<\/strong>
\nPeritoneal effusion: Pancreatic carcinoma. 20x<\/div>\n<\/div>\n
Figure 111<\/strong>
\nPeritoneal effusion:
\nPancreatic carcinoma.
\n20x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 112<\/strong>
\nPeritoneal effusion: Pancreatic carcinoma. 40x<\/div>\n<\/div>\n
Figure 112<\/strong>
\nPeritoneal effusion:
\nPancreatic carcinoma.
\n40x<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 113 <\/strong>
\nPeritoneal effusion: Pancreatic carcinoma. 60x<\/div>\n<\/div>\n
Figure 113<\/strong>
\nPeritoneal effusion:
\nPancreatic carcinoma.
\n60x<\/div>\n<\/div>\n
<\/div>\n

Fig 111-113: Peritoneal effusion: Pancreatic carcinoma.<\/strong>
\nPancreatobiliary tumors cause obstruction and elicit a hard fibrous host response. Rarely they may liberate cells into the peritoneal cavity, most likely after omental invasion.[\/vc_column_text][vc_column_text css=”.vc_custom_1500390293825{margin-top: 30px !important;}” el_class=”back-to-top”]Back to Top<\/a><\/strong>[\/vc_column_text][\/vc_column][vc_column width=”1\/3″ offset=”vc_hidden-sm vc_hidden-xs”][vc_widget_sidebar sidebar_id=”consulting-right-sidebar”][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"

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