{"id":1976,"date":"2017-07-31T19:53:39","date_gmt":"2017-07-31T19:53:39","guid":{"rendered":"http:\/\/cytologystuff1.wpengine.com\/non-gyn-atlas\/effusions-metastatic-breast-cancer\/"},"modified":"2025-02-10T20:03:06","modified_gmt":"2025-02-10T20:03:06","slug":"effusions-metastatic-breast-cancer","status":"publish","type":"page","link":"https:\/\/cytologystuff.com\/zh-hans\/non-gyn-atlas\/effusions-metastatic-breast-cancer\/","title":{"rendered":"Effusions – Metastatic Breast Cancer"},"content":{"rendered":"

[vc_row 0=””][vc_column 0=”” offset=”vc_hidden-lg vc_hidden-md”][vc_raw_html 0=””]JTNDY2VudGVyJTNFJTNDYSUyMGNsYXNzJTNEJTIyc2hpZnRuYXYtdG9nZ2xlJTIwc2hpZnRuYXYtdG9nZ2xlLWJ1dHRvbiUyMiUyMGRhdGEtc2hpZnRuYXYtdGFyZ2V0JTNEJTIyc2hpZnRuYXYtbWFpbiUyMiUzRSUzQ2klMjBjbGFzcyUzRCUyMmZhJTIwZmEtYmFycyUyMiUzRSUzQyUyRmklM0UlMjBUYWJsZSUyMG9mJTIwQ29udGVudHMlMjAlM0MlMkZhJTNFJTNDJTJGY2VudGVyJTNF[\/vc_raw_html][\/vc_column][\/vc_row][vc_row][vc_column][vc_custom_heading text=”Cytology of Pleural, Pericardial and Peritoneal Cavity Effusions – Metastatic Breast Cancer” font_container=”tag:h1|text_align:center” use_theme_fonts=”yes”][\/vc_column][\/vc_row][vc_row el_id=”acknowledgements”][vc_column width=”2\/3″][vc_column_text]<\/a><\/p>\n

EFFUSIONS – METASTATIC BREAST CANCER<\/p>\n

Advanced breast cancer metastatic to the liver and peritoneal cavity may induce a peritoneal effusion. The cancer cells are easily distinguished from inflammatory cells and benign mesothelial cells. As in pleural effusions, these cells tend to be present in large rounded clusters as well as individual cells.<\/p>\n

<\/a><\/p>\n

\n

Reminder: You may click on any slide image
\nfor an enlarged view.<\/strong><\/p>\n


\n\"Image<\/a><\/p>\n
Figure 70<\/strong>
\nPeritoneal effusion: Metastatic carcinoma of the breast. Many small clusters and single malignant cells contrast with benign mesothelial cells. 20X<\/div>\n<\/div>\n
Figure 70<\/strong>
\nPeritoneal effusion:
\nMetastatic carcinoma of the breast. Many small clusters and single malignant cells contrast with benign mesothelial cells.
\n20X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 71<\/strong>
\nPeritoneal effusion: Metastatic carcinoma of the breast. Note cells with targetoid intracytoplasmic vacuoles containing mucin droplets. 40X<\/div>\n<\/div>\n
Figure 71<\/strong> Peritoneal effusion:
\nMetastatic carcinoma of the breast. Note cells with targetoid intracytoplasmic vacuoles containing mucin droplets.
\n40X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 72<\/strong>
\nPeritoneal effusion: Metastatic carcinoma of the breast. Note malignant cells contrasting with benign histiocytes. Note large intracytoplasmic vacuoles with mucin droplets. 60X<\/div>\n<\/div>\n
Figure 72<\/strong>
\nPeritoneal effusion:
\nMetastatic carcinoma of the breast. Note malignant cells contrasting with benign histiocytes. Note large intracytoplasmic vacuoles with mucin droplets.
\n60X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 73<\/strong>
\nPleural effusion: Metastatic ductal carcinoma 40X<\/div>\n<\/div>\n
Figure 73<\/strong>
\nPleural effusion:
\nMetastatic ductal carcinoma
\n40X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 74<\/strong>
\nPleural effusion: Metastatic ductal carcinoma 60X<\/div>\n<\/div>\n
Figure 74<\/strong>
\nPleural effusion:
\nMetastatic ductal carcinoma
\n60X<\/div>\n
<\/div>\n

Figures 73-74: Pleural effusion: Metastatic ductal carcinoma.<\/strong>
\nA cluster of metastatic ductal carcinoma cells exhibits large irregular nuclei and nucleoli with a background lymphocytes.<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 75<\/strong>
\nPleural effusion: Metastatic ductal carcinoma. Note this single cell expressing nuclear gigantism. 60X<\/div>\n<\/div>\n
Figure 75<\/strong>
\nPleural effusion:
\nMetastatic ductal carcinoma. Note this single cell expressing nuclear gigantism.
\n60X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 76<\/strong>
\nPleural effusion: Metastatic carcinoma of the breast. 10X<\/div>\n<\/div>\n
Figure 76<\/strong>
\nPleural effusion:
\nMetastatic carcinoma of the breast.
\n10X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 77<\/strong>
\nPleural effusion: Metastatic carcinoma of the breast. 20X<\/div>\n<\/div>\n
Figure 77<\/strong>
\nPleural effusion:
\nMetastatic carcinoma of the breast.
\n20X<\/div>\n
<\/div>\n

Figures 76-77: Pleural effusion: Metastatic carcinoma of the breast.<\/strong>
\nThe classic description of metastatic breast cancer in pleural effusions employs the term “cannonballs” to emphasize the rounded arrangement of tumor cells. Note the relatively small nuclear size. Nuclei are vesicular with prominent nucleoli. Cytoplasmic vacuoles are uncommon. A cell block of the cells allows for assay of hormonal receptors or other epithelial markers, such as her-2-neu.<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 78<\/strong>
\nPeritoneal effusion: Metastatic carcinoma of the breast. Peritoneal effusion showing clusters of large tumor cells. The glandular nature of the tumor is obvious, but origin from breast is not easily determined. 40X<\/div>\n<\/div>\n
Figure 78<\/strong>
\nPeritoneal effusion:
\nMetastatic carcinoma of the breast. Peritoneal effusion showing clusters of large tumor cells. The glandular nature of the tumor is obvious, but origin from breast is not easily determined.
\n40X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 79<\/strong>
\nPleural effusion: Metastatic carcinoma of the breast. Note two separate cell populations: a smaller benign population of mesothelial cells and larger tumor cells. 20X<\/div>\n<\/div>\n
Figure 79<\/strong>
\nPleural effusion:
\nMetastatic carcinoma of the breast. Note two separate cell populations: a smaller benign population of mesothelial cells and larger tumor cells.
\n20X<\/div>\n<\/div>\n
<\/div>\n

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