{"id":1969,"date":"2017-07-31T19:32:51","date_gmt":"2017-07-31T19:32:51","guid":{"rendered":"http:\/\/cytologystuff1.wpengine.com\/non-gyn-atlas\/effusions-mesothelioma\/"},"modified":"2025-02-10T20:03:06","modified_gmt":"2025-02-10T20:03:06","slug":"effusions-mesothelioma","status":"publish","type":"page","link":"https:\/\/cytologystuff.com\/zh-hans\/non-gyn-atlas\/effusions-mesothelioma\/","title":{"rendered":"Effusions – Mesothelioma"},"content":{"rendered":"

[vc_row 0=””][vc_column 0=”” offset=”vc_hidden-lg vc_hidden-md”][vc_raw_html 0=””]JTNDY2VudGVyJTNFJTNDYSUyMGNsYXNzJTNEJTIyc2hpZnRuYXYtdG9nZ2xlJTIwc2hpZnRuYXYtdG9nZ2xlLWJ1dHRvbiUyMiUyMGRhdGEtc2hpZnRuYXYtdGFyZ2V0JTNEJTIyc2hpZnRuYXYtbWFpbiUyMiUzRSUzQ2klMjBjbGFzcyUzRCUyMmZhJTIwZmEtYmFycyUyMiUzRSUzQyUyRmklM0UlMjBUYWJsZSUyMG9mJTIwQ29udGVudHMlMjAlM0MlMkZhJTNFJTNDJTJGY2VudGVyJTNF[\/vc_raw_html][\/vc_column][\/vc_row][vc_row][vc_column][vc_custom_heading text=”Cytology of Pleural, Pericardial and Peritoneal Cavity Effusions – Effusions Mesothelioma” font_container=”tag:h1|text_align:center” use_theme_fonts=”yes”][\/vc_column][\/vc_row][vc_row el_id=”acknowledgements”][vc_column width=”2\/3″][vc_column_text]<\/a><\/p>\n

EFFUSIONS – MESOTHELIOMA<\/p>\n

<\/a><\/p>\n

\n

Reminder: You may click on any slide image
\nfor an enlarged view.<\/strong><\/p>\n


\n\"Image<\/a><\/p>\n
Figure 22<\/strong>
\nPleural effusion Mesothelioma. 10X<\/div>\n<\/div>\n
Figure 22
\n<\/strong>Pleural effusion:
\nMesothelioma.
\n10X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 23<\/strong>
\nPleural effusion Mesothelioma. 20X<\/div>\n<\/div>\n
Figure 23
\n<\/strong> Pleural effusion:
\nMesothelioma.
\n20X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 24<\/strong>
\nPleural effusion Mesothelioma. 40X<\/div>\n<\/div>\n
Figure 24<\/strong>
\nPleural effusion:
\nMesothelioma.
\n40X<\/div>\n
<\/div>\n

Figures 22-24:<\/strong>
\nVarious magnifications show “cannon-ball” masses of tumor cells. The key to diagnosing mesothelioma is not identifying a second malignant cell population. Final determination may require immunocytochemistry or a cell block with immunohistochemistry, electron microscopy, or other specialized techniques.<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 25<\/strong>
\nPleural effusion Mesothelioma. 60X<\/div>\n<\/div>\n
Figure 25<\/strong>
\nPleural effusion:
\nMesothelioma.
\n60X<\/div>\n
<\/div>\n

Individual malignant mesothelial cells exhibit a rim of ruffled, less dense cytoplasm (ectoplasm), surrounding dense cytoplasm around the nucleus (endoplasm).<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 26<\/strong>
\nPleural effusion Mesothelioma. 20X<\/div>\n<\/div>\n
Figure 26<\/strong>
\nPleural effusion:
\nMesothelioma.
\n20X<\/div>\n
<\/div>\n

Tumor cells may be seen in a background of blood and proteinaceous debris. Groups of more than 12 cells may be a feature of malignancy.<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 27<\/strong>
\nPleural effusion Mesothelioma. 60X<\/div>\n<\/div>\n
Figure 27<\/strong>
\nPleural effusion:
\nMesothelioma.
\n60X<\/div>\n
<\/div>\n

At higher magnification, the high N\/C ratio with variability in nuclear size and occasional multi-nucleation confirm the malignant nature of these cells. Differential diagnoses include adenocarcinoma and mesothelioma. Fine microscopic features of peripheral cell membranes and intercellular windows may suggest mesothelioma.<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 28<\/strong>
\nPleural effusion Mesothelioma. 60X<\/div>\n<\/div>\n
Figure 28<\/strong>
\nPleural effusion:
\nMesothelioma.
\n60X<\/div>\n<\/div>\n
<\/div>\n

Abnormal mitotic figures may be noted with mesothelioma, other malignancies, as well as occasional reactive mesothelial cells in effusions.[\/vc_column_text][vc_column_text el_class=”back-to-top”]Back to Top<\/a><\/strong>[\/vc_column_text][\/vc_column][vc_column width=”1\/3″ offset=”vc_hidden-sm vc_hidden-xs”][vc_widget_sidebar sidebar_id=”consulting-right-sidebar”][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"

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