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Unknown Case - January, 2014 Part 2

Transitional Metaplasia

Transitional metaplasia is often associated with atrophy. It mainly consists of cohesive sheets of parabasal cells with high N/C ratios that can be spindle-shaped and appear to be streaming. Distinct cell borders are noted. The nuclei are oval with nuclear grooves, finely granular chromatin and indistinct nucleoli. Perinuclear halos can be seen. Differential diagnoses include tubal metaplasia, atrophy and HSIL.

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Patient information: 58 year old female, LMP 2 years ago

Specimen type: ThinPrep Pap Test


Case provided by Long Island Jewish Medical Center, Long Island, New York.

References
  1. DeMay, Mac: Practical Principles of Cytopathology. 1999: 2
  2. DeMay, Mac: The Art & Science of Cytopathology Second Edition. 2012: 76